Colistin only sensitive Acinetobacter baumanii infection involving prosthetic joints

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Inhaled Colistin for Treatment of Pneumonia due to Colistin-Only-Susceptible Acinetobacter baumannii

PURPOSE Colistin is used for the treatment of pneumonia associated with multidrug- resistant Acinetobacter baumannii and Pseudomonas aeruginosa. However, the best route of administration and dosage is not known. We report our experience with aerosolized colistin in twelve patients with pneumonia caused by colistin-only-susceptible (COS) A. baumannii. MATERIALS AND METHODS We retrospectively r...

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Acinetobacter spp. has emerged as a significant hospital pathogen, quickly becoming resistant to commonly used routine drugs. Colistin remains as the only drug of choice for carbapenem resistant Acinetobacter. In our study among 65 strains of Acinetobacter isolated from different clinical samples, 2 strains showed Colistin resistance by Disk diffusion method .It was confirmed by performing mini...

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Successful treatment of multicompartmental cerebral ventriculitis caused by Acinetobacter baumanii

We present a case report of a 58-year- old woman with subarachnoid haemorrhage complicated by non-communicating hydrocephalus. During the course of her neurosurgical management, she developed external-ventricular drain associated ventriculitis which in turn was complicated by lack of communication between third and fourth ventricles. The causative organism was a fully-sensitive Acinetobacter ba...

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Global Epidemiology on Colistin Resistant Acinetobacter baumannii

While colistin remains a last resort agent to treat multi-drug resistant Acinetobacter baumannii, resistance to colistin has been reported throughout the world. The resistance has been attributed to mutations in lipid A biosynthesis genes and point mutation in PmrAB-two component response regulator and sensor kinase system. The emergence of plasmid mediated colistin resistance (mcr-1), in multi...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2016

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2016.11.120